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132854-36-5 , a-Naphthyl phosphate disodium salt hydrate

132854-36-5, a-Naphthyl phosphate disodium salt hydrate;
1-Naphthalenol dihydrogen phosphate disodium salt; 1-Naphthyl disodium orthophosphate,
Cas:132854-36-5
C10H7O4PNa2 / 268.11(as anhydrous)
MFCD00041007

a-Naphthyl phosphate disodium salt hydrate

1-Naphthalenol dihydrogen phosphate disodium salt; 1-Naphthyl disodium orthophosphate

a-Naphthyl phosphate disodium salt hydrate (APDS) is a potent inhibitor of phosphatases, which are enzymes that catalyze the hydrolysis of phosphoric acid esters. APDS inhibits the formation rate of polyphosphate in cells and has been shown to inhibit the mineralization of bone by osteoclasts. APDS binds to polyphosphate and prevents its polymerization, inhibiting cell growth. This drug also inhibits enzyme activity in biological products such as DNA and RNA polymerases, ribosomes, and histidine decarboxylase.

CAS Number132854-36-5
Product NameSodium naphthalen-1-yl phosphate hydrate
Molecular FormulaC10H11Na2O5P
Molecular Weight288.146
InChIInChI=1S/C10H9O4P.2Na.H2O/c11-15(12,13)14-10-7-3-5-8-4-1-2-6-9(8)10;;;/h1-7H,(H2,11,12,13);;;1H2
InChI KeyITDOXWAUHXVEJT-UHFFFAOYSA-N
SMILESC1=CC=C2C(=C1)C=CC=C2OP(=O)(O)O.O.[Na].[Na]


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