92051-23-5 ,tetra-O-acetyl-2-O-triflat-beta-D-mannopyranose,
CAS:92051-23-5
C15H19F3O12S / 480.37
MFCD00012353
四乙酰基-b-D-甘露糖-2-三氟甲磺酸酯,
1,3,4,6-Tetra-O-acetyl-2-O-trifluoromethanesulfonyl-b-D-mannopyranose is a chemical compound that belongs to the group of fatty acids. It is a product of chemical reactions and has been shown to be able to react with positrons in an organic solution. This compound can also react with potassium ions in water vapor. The reaction solution is suitable for testing samples and cell culture.
Mannose triflate is a compound used in various scientific experiments and research activities to help understand its physical and chemical properties, synthesis, characterization, and biological properties. The compound is also used in different industries, including the food and pharmaceutical industries. The following paper aims to provide a comprehensive overview of Mannose triflate, including its definition and background, physical and chemical properties, synthesis and characterization, analytical methods, biological properties, toxicity and safety in scientific experiments, applications in scientific experiments, current state of research, potential implications in various fields of research and industry, limitations, and future directions.
Synthesis and Characterization:
Mannose triflate can be synthesized through several methods, including the triflation of Mannose with TfOCl/TfOH, Tf2O/TfOH, Tf2O/sulfonic acid, and Tf2O/pyridine. The synthesis of Mannose triflate involves the use of triflate reagents, which are highly reactive and can react with various nucleophiles. Therefore, the synthesis of Mannose triflate requires careful control of reaction conditions to prevent side reactions and ensure high yield.
The characterization of Mannose triflate can be done using various techniques, including NMR spectroscopy, mass spectrometry, and X-ray crystallography. NMR spectroscopy is one of the most commonly used techniques for the characterization of Mannose triflate, as it can provide information about the chemical structure and purity of the compound.
Analytical Methods:
Several analytical methods can be used to detect and quantify Mannose triflate, including high-performance liquid chromatography, gas chromatography, and mass spectrometry. These methods are used to determine the purity of Mannose triflate, its stability, and its concentration in different samples.
Biological Properties:
Mannose triflate has been shown to possess several biological properties, including anti-inflammatory, antioxidant, and antitumor activities. The compound has been studied extensively in vitro and in vivo to determine its potential therapeutic applications. Studies have shown that Mannose triflate can inhibit the growth of various cancer cells, including prostate, breast, and lung cancer cells, by inducing apoptosis and inhibiting cell proliferation.
Toxicity and Safety in Scientific Experiments:
Due to its potential therapeutic applications, Mannose triflate is widely used in scientific experiments. However, the toxicity and safety of Mannose triflate in experimental animals and humans are still not fully understood. Studies have shown that Mannose triflate is relatively non-toxic, with a low acute toxicity and no adverse effects on key organs such as the liver and kidneys. However, more studies are needed to evaluate the long-term effects of Mannose triflate on the human body.
Applications in Scientific Experiments:
Mannose triflate has a wide range of applications in scientific experiments, including its use as a glycosylation reagent, a carbohydrate building block, and an anticancer agent. Mannose triflate is also used in the food and pharmaceutical industries, where it is added as a sweetener and flavor enhancer.
Current State of Research:
Mannose triflate is a compound that is currently the focus of extensive research in various fields, including the pharmaceutical, chemical, and biological sciences. Studies are ongoing to understand its mechanism of action, its potential therapeutic applications, and its safety profile in humans.
Potential Implications in Various Fields of Research and Industry:
Mannose triflate has the potential to revolutionize various fields of research and industry, including the development of new anticancer drugs, carbohydrate-based vaccines, and glycomimetics. The compound can also be used in the food industry as a safe, natural, and low-calorie sweetener.
Limitations and Future Directions:
Despite the promising potential of Mannose triflate in various applications, there are several limitations that need to be addressed. These include the need for further studies to improve its stability and solubility, its toxicity and safety profile in humans, and its pharmacokinetic properties. Future directions for research on Mannose triflate include the development of new synthesis techniques, the identification of its potential targets, and the evaluation of its long-term effects on human health.
Conclusion:
Mannose triflate is a compound with various potential applications in scientific experiments and various industries. The compound has several properties, including physical, chemical, and biological properties, and its potential therapeutic applications are still being explored. More studies are required to determine its safety and toxicity profile in humans, improve its pharmacokinetic properties, and identify its potential targets. Despite these limitations, Mannose triflate has the potential to revolutionize various fields of research and industry and provide novel solutions to some of the world's most critical challenges.
CAS Number | 92051-23-5 |
Product Name | Mannose triflate |
IUPAC Name | [(2R,3R,4S,5S,6S)-3,4,6-triacetyloxy-5-(trifluoromethylsulfonyloxy)oxan-2-yl]methyl acetate |
Molecular Formula | C15H19F3O12S |
Molecular Weight | 480.37 g/mol |
InChI | InChI=1S/C15H19F3O12S/c1-6(19)25-5-10-11(26-7(2)20)12(27-8(3)21)13(14(29-10)28-9(4)22)30-31(23,24)15(16,17)18/h10-14H,5H2,1-4H3/t10-,11-,12+,13+,14-/m1/s1 |
InChI Key | OIBDVHSTOUGZTJ-PEBLQZBPSA-N |
SMILES | CC(=O)OCC1C(C(C(C(O1)OC(=O)C)OS(=O)(=O)C(F)(F)F)OC(=O)C)OC(=O)C |
Synonyms | 1,3,4,6-Tetraacetate 2-(trifluoromethanesulfonate) β-D-Mannopyranose; Mannose Triflate; |
Canonical SMILES | CC(=O)OCC1C(C(C(C(O1)OC(=O)C)OS(=O)(=O)C(F)(F)F)OC(=O)C)OC(=O)C |
Isomeric SMILES | CC(=O)OC[C@@H]1[C@H]([C@@H]([C@@H]([C@@H](O1)OC(=O)C)OS(=O)(=O)C(F)(F)F)OC(=O)C)OC(=O)C |
CAS No: 92051-23-5 Synonyms: 1,3,4,6-Tetraacetate 2-(trifluoromethane-sulphonate)-b-D-mannopyranoseMannose triflateTATM MDL No: MFCD00012353 Chemical Formula: C15H19F3O12S Molecular Weight: 480.37 |
References: 1. Pavliak V, et al., Carbohyr. Res. 1991, No210, p333-337 |
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