87687-03-4 , Resorufin pentyl ether ; 7-(Pentyloxy)-3H-phenoxazin-3-one; 7-Pentoxyresorufin; 7-Pentoxyphenoxazone

87687-03-4 , Resorufin pentyl ether ;
7-(Pentyloxy)-3H-phenoxazin-3-one; 7-Pentoxyresorufin; 7-Pentoxyphenoxazone,
Cas:87687-03-4
C17H17NO3 / 283.32
MFCD00037664

Resorufin pentyl ether

7-(Pentyloxy)-3H-phenoxazin-3-one; 7-Pentoxyresorufin; 7-Pentoxyphenoxazone

Resorufin pentyl ether is a drug transporter that can be used as an experimental model for studying the effects of chemical pesticides on humans. Resorufin pentyl ether inhibits energy metabolism and inhibits hepatic p450 activity and polymerase chain reaction in hepatocyte-like cells in vitro. It has been shown to inhibit the enzyme activities of rat liver p450s and human cytochrome P450 3A4 (CYP3A4) at physiological levels. Resorufin pentyl ether has also been shown to be toxic in mice, with toxicity studies showing an LD50 of 4.5 mg/kg after oral administration. This drug is not active against bacteria or fungi, but it is able to inhibit protein synthesis in model systems containing mouse monoclonal antibodies or calf thymus DNA.

CAS Number	87687-03-4
Product Name	Pentoxyresorufin
IUPAC Name	7-pentoxyphenoxazin-3-one
Molecular Formula	C17H17NO3
Molecular Weight	283.32 g/mol
InChI	InChI=1S/C17H17NO3/c1-2-3-4-9-20-13-6-8-15-17(11-13)21-16-10-12(19)5-7-14(16)18-15/h5-8,10-11H,2-4,9H2,1H3
InChI Key	ZPSOKQFFOYYPKC-UHFFFAOYSA-N
SMILES	CCCCCOC1=CC2=C(C=C1)N=C3C=CC(=O)C=C3O2
Synonyms	7-(Pentyloxy)-3H-phenoxazin-3-one; 7-Pentoxyphenoxazone; 7-Pentoxyresorufin;
Canonical SMILES	CCCCCOC1=CC2=C(C=C1)N=C3C=CC(=O)C=C3O2