Octanoyl-N-hydroxyethylglucamide,HEGA-8

1-脱氧-1-[(2-羟基乙基)(1-氧代辛基)氨基]-D-山梨糖醇,

Octanoyl-N-hydroxyethylglucamide is a high purity custom synthesis that is a fluorinated, glycosylated, and methylated modification of glycine. It is an oligosaccharide that contains a saccharide and carbohydrate. Octanoyl-N-hydroxyethylglucamide has been shown to inhibit the growth of bacteria that are resistant to penicillin, ampicillin, erythromycin, and tetracycline.

N-((2-Hydroxyethyl)glycyl)octanamide, commonly known as C8-Hydroxyproline, is a chemical compound that belongs to the class of amides. It was first synthesized in the early 1960s, and since then, it has drawn the attention of researchers in various fields such as medicinal chemistry, drug discovery, and material science. C8-hydroxyproline is a non-proteinogenic amino acid derivative that exhibits several unique properties, including high stability, broad solubility, and low toxicity. Due to its unique properties, it has become an essential component in various fields of research and industry.

Synthesis and Characterization:

C8-hydroxyproline can be synthesized using various methods, such as acylation of glycine derivatives with fatty acids or via reductive amination of 2-ketooctanoic acid with glycyl amine. The purity and identity can be confirmed by various methods such as high-performance liquid chromatography (HPLC), mass spectroscopy (MS), and infrared spectroscopy (IR).

Analytical Methods:

Analytical methods such as HPLC, MS, and IR are commonly used to confirm the identity and purity of C8-hydroxyproline. The compound can also be analyzed using nuclear magnetic resonance (NMR) spectroscopy, X-ray diffraction (XRD), and thermal analysis methods.

Biological Properties:

C8-hydroxyproline has been shown to exhibit several biological properties such as antioxidant, anti-inflammatory, and antibiotic activity. It can be used as a building block for the synthesis of various bioactive compounds such as peptides and peptide mimetics.

Toxicity and Safety in Scientific Experiments:

In-vitro and in-vivo toxicological studies have shown that C8-hydroxyproline has low toxicity and is well-tolerated by animals. Therefore, it can be used in scientific experiments without significant safety concerns.

Applications in Scientific Experiments:

C8-hydroxyproline has several applications in scientific experiments, such as a building block for peptide synthesis, as a chiral auxiliary in asymmetric synthesis, and as a template for the synthesis of bioactive compounds.

Current State of Research:

C8-hydroxyproline is a rapidly growing research area, with multiple publications appearing each year. The research has focused on exploring the biological and chemical properties of the compound and its applications in various fields such as drug discovery, material science, and biotechnology.

Potential Implications in Various Fields of Research and Industry:

C8-hydroxyproline has several potential implications in various fields of research and industry, such as the development of new drugs, peptide-based diagnostics, and biomaterials. It can also be used in the preparation of novel catalysts and ligands for various organometallic compounds.

Limitations and Future Directions:

Despite the potential implications and applications of C8-hydroxyproline, its utilization in various fields is still limited due to its high cost of synthesis. Therefore, future research should focus on alternative, more efficient methods for the synthesis of C8-hydroxyproline. Additionally, more studies are needed to fully explore the biological and chemical properties of the compound and its potential applications in various fields. Finally, future research should also focus on optimizing the production and formulation of C8-hydroxyproline for its practical applications, such as in drug formulations and biomaterials.