82535-18-0 , Galb1-4GalNAc ; 2-Acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-D-galactopyranose

82535-18-0 , Galb1-4GalNAc ;
2-Acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-D-galactopyranose
C14H25NO11 / 383.35
MFCD12756102

Galb1-4GalNAc

2-Acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-D-galactopyranose

2-Acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-D-galactopyranose is a glycan that binds to human lymphocytes and induces their death. It is a glycan that has been shown to be sialylated, which may be due to its high degree of homology with other glycan structures. The 2-acetamido group confers the ability to bind to sialyltransferases, which are enzymes that catalyze the transfer of sialic acid from glucose onto complex carbohydrates. This binding inhibits the enzymatic activity of these enzymes and prevents the addition of sialic acid onto oligosaccharides, preventing antigen presentation.

CAS Number	82535-18-0
Product Name	2-Acetamido-2-deoxy-4-O-(B-D-galactopyranosyl)-D-galactopyranose
IUPAC Name	N-[(3R,4R,5R,6R)-2,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-3-yl]acetamide
Molecular Formula	C₁₄H₂₅NO₁₁
Molecular Weight	383.35
InChI	InChI=1S/C14H25NO11/c1-4(18)15-7-9(20)12(6(3-17)24-13(7)23)26-14-11(22)10(21)8(19)5(2-16)25-14/h5-14,16-17,19-23H,2-3H2,1H3,(H,15,18)/t5-,6-,7-,8+,9-,10+,11-,12+,13?,14+/m1/s1
SMILES	CC(=O)NC1C(C(C(OC1O)CO)OC2C(C(C(C(O2)CO)O)O)O)O
Synonyms	2-(Acetylamino)-2-deoxy-4-O-β-D-galactopyranosyl-D-galactopyranose;