68652-37-9 , GQ1b-Ganglioside ammonium
Cas:68652-37-9
C106H182N6O56·xNH4 / 2504.732
GQ1b-Ganglioside is a glycosphingolipid, a type of lipid molecule containing a carbohydrate portion. It is a ganglioside, a class of glycosphingolipids that contain sialic acid. GQ1b-Ganglioside is found on the surface of certain nervous system cells such as neurons and Schwann cells. It plays a role in cellular signaling and recognition.
Physical and Chemical Properties
GQ1b-Ganglioside is a complex molecule with a molecular weight of approximately 1,350 Daltons. It contains a ceramide portion and various sugar residues, including sialic acid, glucose, and galactose. GQ1b-Ganglioside is soluble in water and organic solvents such as chloroform and methanol.
Synthesis and Characterization
GQ1b-Ganglioside can be synthesized in the laboratory using a variety of chemical and enzymatic methods. The synthesis typically involves the construction of the ceramide portion of the molecule followed by the addition of the sugar residues in a specific order.
Analytical Methods
Several analytical methods are used to characterize GQ1b-Ganglioside, including mass spectrometry, nuclear magnetic resonance spectroscopy, and thin-layer chromatography. These methods can be used to determine the purity and identity of the molecule.
Biological Properties
GQ1b-Ganglioside plays a significant role in the pathology of certain nerve disorders, including Guillain-Barre syndrome and Miller Fisher syndrome. Antibodies to GQ1b-Ganglioside are produced in these disorders, leading to nerve damage and dysfunction. GQ1b-Ganglioside is also involved in cellular signaling and recognition, playing a role in the immune response and the nervous system.
Toxicity and Safety in Scientific Experiments
GQ1b-Ganglioside has been shown to be non-toxic in scientific studies. However, as with any biological substance, caution must be exercised in handling and disposing of the substance.
Applications in Scientific Experiments
GQ1b-Ganglioside is used in a variety of scientific experiments, including studies of the nervous system, the immune response, and cellular signaling. GQ1b-Ganglioside is also used in the development of diagnostic tests for certain nerve disorders.
Current State of Research
Research on GQ1b-Ganglioside is ongoing, with a focus on understanding its role in nerve disorders and its potential as a therapeutic target. Researchers are also exploring the use of GQ1b-Ganglioside in the development of new diagnostic tests and treatments for nerve disorders.
Potential Implications in Various Fields of Research and Industry
The potential implications of GQ1b-Ganglioside are broad, with potential applications in the fields of medicine, biotechnology, and materials science. GQ1b-Ganglioside may be useful in the development of nerve repair therapies, immunotherapies, and diagnostic tests. It may also have applications in the development of new materials and technologies.
Limitations and Future Directions
Limitations of GQ1b-Ganglioside include its complexity and the difficulty in synthesizing it in large quantities. Future research directions include the development of new methods for synthesizing GQ1b-Ganglioside and the exploration of its potential therapeutic applications in nerve disorders. Additional research is also needed to better understand the role of GQ1b-Ganglioside in cellular signaling and recognition.
Future Directions:
1. Explore the potential of GQ1b-Ganglioside in other fields such as food science and cosmetics.
2. Develop new methods for identifying and targeting GQ1b-Ganglioside in the immune system.
3. Investigate the relationship between GQ1b-Ganglioside and other glycosphingolipids in the nervous system.
4. Develop new therapies based on GQ1b-Ganglioside for nerve disorders.
5. Investigate the potential of GQ1b-Ganglioside in the development of new materials and technologies.
6. Explore the use of GQ1b-Ganglioside in the treatment of other diseases such as cancer and autoimmune disorders.
7. Investigate the role of GQ1b-Ganglioside in cellular differentiation and development.
8. Develop new analytical methods for studying GQ1b-Ganglioside in biological samples.
9. Explore the potential of GQ1b-Ganglioside as a biomarker for nerve disorders.
10. Investigate the possibility of using GQ1b-Ganglioside as a targeted drug delivery system.
CAS Number | 68652-37-9 |
Product Name | GQ1b-Ganglioside |
IUPAC Name | (2S,4S,5R,6R)-5-acetamido-2-[(2S,3R,4R,5R,6R)-3-acetamido-5-[(2S,3R,4S,5S,6R)-4-[(2S,4S,5R,6R)-5-acetamido-2-carboxy-6-[(1S,2R)-2-[(2S,4S,5R,6R)-2-carboxy-4-hydroxy-5-[(2-hydroxyacetyl)amino]-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy-1,3-dihydroxypropyl]-4-hydroxyoxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[(2R,3R,4R,5R,6S)-6-[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(E,2S,3R)-3-hydroxy-2-(octadecanoylamino)octadec-4-enoxy]oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxan-4-yl]oxy-6-[(1S,2R)-2-[(2S,4S,5R,6R)-5-acetamido-2-carboxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy-1,3-dihydroxypropyl]-4-hydroxyoxane-2-carboxylic acid;azane |
Molecular Formula | C106H194N10O56 |
Molecular Weight | 2504.732 |
InChI | InChI=1S/C106H182N6O56.4H3N/c1-7-9-11-13-15-17-19-21-22-24-26-28-30-32-34-36-69(133)111-55(56(126)35-33-31-29-27-25-23-20-18-16-14-12-10-8-2)50-153-96-83(142)81(140)87(66(46-118)156-96)159-97-84(143)82(141)86(67(47-119)157-97)158-95-75(110-54(6)125)93(167-105(101(149)150)39-58(128)72(108-52(4)123)91(165-105)79(138)64(44-116)161-103(99(145)146)37-57(127)71(107-51(3)122)89(163-103)76(135)61(131)41-113)88(68(48-120)155-95)160-98-85(144)94(78(137)63(43-115)154-98)168-106(102(151)152)40-59(129)73(109-53(5)124)92(166-106)80(139)65(45-117)162-104(100(147)148)38-60(130)74(112-70(134)49-121)90(164-104)77(136)62(132)42-114;;;;/h33,35,55-68,71-98,113-121,126-132,135-144H,7-32,34,36-50H2,1-6H3,(H,107,122)(H,108,123)(H,109,124)(H,110,125)(H,111,133)(H,112,134)(H,145,146)(H,147,148)(H,149,150)(H,151,152);4*1H3/b35-33+;;;;/t55-,56+,57-,58-,59-,60-,61+,62+,63+,64+,65+,66+,67+,68+,71+,72+,73+,74+,75+,76+,77+,78-,79+,80+,81+,82+,83+,84+,85+,86-,87+,88-,89+,90+,91+,92+,93+,94-,95-,96+,97-,98-,103+,104+,105-,106-;;;;/m0..../s1 |
InChI Key | IOULOLQJODJAEM-BSALKOQBSA-N |
SMILES | CCCCCCCCCCCCCCCCCC(=O)NC(COC1C(C(C(C(O1)CO)OC2C(C(C(C(O2)CO)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)CO)O)OC5(CC(C(C(O5)C(C(CO)OC6(CC(C(C(O6)C(C(CO)O)O)NC(=O)CO)O)C(=O)O)O)NC(=O)C)O)C(=O)O)O)OC7(CC(C(C(O7)C(C(CO)OC8(CC(C(C(O8)C(C(CO)O)O)NC(=O)C)O)C(=O)O)O)NC(=O)C)O)C(=O)O)NC(=O)C)O)O)O)O)C(C=CCCCCCCCCCCCCC)O.N.N.N.N |
Synonyms | ganglioside GQ1b, tetrasodium salt |
Contact: Miss.Xing
Phone: 18310328607 , 13621067991,13552979007
Tel: 86+10-61274189
Email: chemsynlab@163.com, zhangchao@chemsynlab.com
Add: A411 Room,No.26,Jinyuan Road,Daxing Industrial Developing District,Beijing,China post code:102628