64664-99-9 , 3-Carboxyumbelliferyl b-D-galactopyranoside , CUG; Carboxyumbelliferyl b-D-galactoside

Cas:64664-99-9 ,
3-Carboxyumbelliferyl b-D-galactopyranoside ,
CUG; Carboxyumbelliferyl b-D-galactoside
C16H16O10 / 368.28
MFCD00153934

3-Carboxyumbelliferyl b-D-galactopyranoside , CUG;

Carboxyumbelliferyl b-D-galactoside

3-Carboxyumbelliferyl b-D-galactopyranoside is a fluorescent probe that can be used to study protein synthesis in live cells. It binds to the active site of the enzyme peptidyl transferase, which catalyzes the covalent linkage of amino acids to form a polypeptide chain. 3CMBG is specific for the amino acid proline and is a substrate for peptidyl transferase. The fluorescence of 3CMBG increases when it is bound to peptidyl transferase, making it useful as a marker for protein synthesis.

CUG (3-Carboxyumbelliferyl-β-D-galactopyranoside) is a fluorogenic substrate (λex=386, λem=445 nm, ε=32K).

CAS Number	64664-99-9
Product Name	3-Carboxyumbelliferyl beta-D-galactopyranoside
IUPAC Name	2-oxo-7-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromene-3-carboxylic acid
Molecular Formula	C₁₆H₁₆O₁₀
Molecular Weight	368.29 g/mol
InChI	InChI=1S/C16H16O10/c17-5-10-11(18)12(19)13(20)16(26-10)24-7-2-1-6-3-8(14(21)22)15(23)25-9(6)4-7/h1-4,10-13,16-20H,5H2,(H,21,22)/t10-,11+,12+,13-,16-/m1/s1
InChI Key	HGMXXIAQZWTZLR-WUGLTUCPSA-N
SMILES	C1=CC2=C(C=C1OC3C(C(C(C(O3)CO)O)O)O)OC(=O)C(=C2)C(=O)O
Canonical SMILES	C1=CC2=C(C=C1OC3C(C(C(C(O3)CO)O)O)O)OC(=O)C(=C2)C(=O)O
Isomeric SMILES	C1=CC2=C(C=C1O[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O)O)OC(=O)C(=C2)C(=O)O