L-Mannitol, L-甘露糖醇

L-Mannitol is a sugar alcohol that is an important component of pharmaceutical preparations. It is used as a preservative, diluent, and sweetener in many pharmaceutical products. L-Mannitol has been shown to have anti-inflammatory properties and may help prevent allergic reactions by inhibiting the production of prostaglandin D2. L-Mannitol also inhibits the activity of xylitol dehydrogenase, which prevents the conversion of xylitol to DHA, an intermediate metabolite that can cause tissue damage in animals and humans. L-Mannitol has been shown to have a laxative effect when taken orally or injected as an intravenous solution. This property may be due to its ability to stimulate chloride secretion from intestinal cells and increase water reabsorption from the colon. L-Mannitol is also used as a chromatographic matrix for saponins and conjugates with other amino acids.