498-94-2, Isonipecotic acid, 4-Piperidinecarboxylic acid, Hexahydroisonicotinic acid, CAS:498-94-2

498-94-2, Isonipecotic acid,
4-Piperidinecarboxylic acid,
Hexahydroisonicotinic acid,
CAS:498-94-2
C6H11NO2 / 129.16
MFCD00006004

4-哌啶甲酸, 哌啶-4-甲酸,Isonipecotic acid

Isonipecotic acid

Isonipecotic acid is a potent antagonist that binds to the response element of the platelet cyclic adenosine monophosphate (cAMP) receptor. This receptor is a regulatory protein that controls the activity of cAMP in cells, including platelets. Isonipecotic acid can be used to treat coronary heart diseases and autoimmune diseases by regulating blood clotting, as well as for treatment of insect resistance and autoimmune diseases. It has been shown to have pharmacokinetic properties that are similar to those of other coumarin derivatives.

CAS Number	498-94-2
Product Name	Isonipecotic acid
IUPAC Name	piperidine-4-carboxylic acid
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
InChI	InChI=1S/C6H11NO2/c8-6(9)5-1-3-7-4-2-5/h5,7H,1-4H2,(H,8,9)
InChI Key	SRJOCJYGOFTFLH-UHFFFAOYSA-N
SMILES	C1CNCCC1C(=O)O
Synonyms	Isonipecoticacid;Piperidine-4-carboxylicacid;498-94-2;4-Piperidinecarboxylicacid;Hexahydroisonicotinicacid;4-Carboxypiperidine;dl-isopipecolinicacid;Isonicotinicacid,hexahydro-;iso-nipecoticacid;4-Hexahydroisonicotinicacid;Acideisonipecotique;h-pic(4)-oh;UNII-M5TZP1RWIE;NSC61049;Acideisonipecotique[French];CHEMBL279998;Acidepiperidine-carboxylique-4;SRJOCJYGOFTFLH-UHFFFAOYSA-N;EINECS207-872-3;MFCD00006004;BRN0112553;Acidepiperidine-carboxylique-4[French];h-inp-oh;isonipecolinicacid;4-carboxy-piperidine
Canonical SMILES	C1C[NH2+]CCC1C(=O)[O-]

Title: Isonipecotic Acid

CAS Registry Number: 498-94-2

CAS Name: 4-Piperidinecarboxylic acid

Additional Names: hexahydroisonicotinic acid

Molecular Formula: C6H11NO2

Molecular Weight: 129.16

Percent Composition: C 55.79%, H 8.58%, N 10.84%, O 24.77%

Literature References: Prepd by reduction of isonicotinic acid in glacial acetic acid in the presence of platinum oxide: Wibaut, Rec. Trav. Chim. 63, 141 (1944); by reduction of isonicotinic acid in H2O and concd HCl with PtO2: Sperber et al., US 2739968 (1956 to Schering); Freifelder, US 3159639 (1964 to Abbott).