488-81-3, Adonitol,Ribitol,
CAS:488-81-3
C5H12O5 / 152.15
MFCD00064291
Ribitol is a pentose sugar alcohol derived from ribose in vivo via the pentose phosphate pathway. It is a component of the glycopolymer teichoic acid in bacterial cell walls. Levels of ribitol are increased in the brain, cerebrospinal fluid, urine, and plasma of a patient with ribose-5-phosphate isomerase (RPI) deficiency, an extremely rare inborn error of metabolism characterized by a heterozygous frameshift mutation and missense allele in the RPI gene leading to leukoencephalopathy and mild peripheral polyneuropathy.
Title: Adonitol
CAS Registry Number: 488-81-3
CAS Name: Ribitol
Additional Names: adonite
Molecular Formula: C5H12O5
Molecular Weight: 152.15
Percent Composition: C 39.47%, H 7.95%, O 52.58%
Literature References: A pentitol from Adonis vernalis L., Ranunculaceae; also from A. amurensis L., Ranunculaceae: Santavy, Reichstein, Pharm. Acta Helv. 23, 153 (1948).
Properties: Large, optically inactive crystals. mp 102°. Does not reduce Fehling's soln. Freely soluble in water, hot alcohol; insol in ether.
Melting point: mp 102°
CAS Number | 488-81-3 |
Product Name | Ribitol |
IUPAC Name | (2S,4R)-pentane-1,2,3,4,5-pentol |
Molecular Formula | C5H12O5 |
Molecular Weight | 152.15 |
InChI | InChI=1S/C5H12O5/c6-1-3(8)5(10)4(9)2-7/h3-10H,1-2H2/t3-,4+,5? |
InChI Key | HEBKCHPVOIAQTA-ZXFHETKHSA-N |
SMILES | C(C(C(C(CO)O)O)O)O |
Solubility | Soluble in DMSO |
Synonyms | Ribitol, Adonitol, NSC 16868 |
CAS No: 488-81-3 Synonyms: Adonitol MDL No: MFCD00064291 Chemical Formula: C5H12O5 Molecular Weight: 152.15 | IN Stock.现货 |
COA: |
Product name: Adonitol;Ribitol CAS: 488-81-3 M.F.: C5H12O5 M.W.: 152.15
Items | Standards | Results |
Appearance | A white solid | Positive |
Solubility | Easily soluble in H2O and less soluble in petroleum ether | Complies |
Appearance of solution | Dissolve 0.5 gin 10 ml of water, and the solution should be clear | Complies |
NMR and ESI-MS | Should comply | Complies |
Identification | IR and TLC | Positive |
M.P. | 100℃ - 102℃ | 100℃ - 102℃ |
Residue on ignition | Max. 0.5% | 0.05% |
Heavy metal | Max. 20ppm | Complies |
TLC (15%H2SO4-C2H5OH) | One spot | Complies |
Assay | Min. 98% | 99.2% |
References:
1. de Valdéz GF, de Giori GS, de Ruiz Holgado AAP, Oliver G, Appl. Environ. Microbiol. 1983, p302–304
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