3947-62-4 , 2,3,4,6-O-Tetraacetyl-D-glucose; Tetraacetyl-D-glucose,
CAS:3947-62-4
C14H20O10 / 348.303
MFCD00061634
2,3,4,6-O-四乙酰基-D-葡萄糖,
2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranose is a synthetic compound that is used as an oral medicine. It has been shown to be effective in the treatment of arthritis and other inflammatory conditions. The preparation process involves the conversion of 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranose into besifloxacin and chiral 2,3,4,6 tetra acetyl beta D glucopyranose. This drug is then recrystallized with potassium carbonate to produce besifloxacin as a white crystalline solid. Recrystallizing this drug produces besifloxacin as a white crystalline solid. 2,3,4,6 Tetra O Acetyl Beta D Glucopyranose can be detected using analytical chemistry methods such as reversed phase liquid.
CAS Number | 3947-62-4 |
Product Name | 2,3,4,6-Tetra-O-acetyl-beta-D-glucose |
IUPAC Name | [(2R,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-hydroxyoxan-2-yl]methyl acetate |
Molecular Formula | C14H20O10 |
Molecular Weight | 348.303 g/mol |
InChI | InChI=1S/C14H20O10/c1-6(15)20-5-10-11(21-7(2)16)12(22-8(3)17)13(14(19)24-10)23-9(4)18/h10-14,19H,5H2,1-4H3/t10-,11-,12+,13-,14-/m1/s1 |
InChI Key | IEOLRPPTIGNUNP-RKQHYHRCSA-N |
SMILES | CC(=O)OCC1C(C(C(C(O1)O)OC(=O)C)OC(=O)C)OC(=O)C |
Canonical SMILES | CC(=O)OCC1C(C(C(C(O1)O)OC(=O)C)OC(=O)C)OC(=O)C |
Isomeric SMILES | CC(=O)OC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)OC(=O)C)OC(=O)C)OC(=O)C |
CAS No: 3947-62-4,10343-06-3 Synonyms: 2,3,4,6-Tetraacetate D-glucopyranose MDL No: MFCD00061634 Chemical Formula: C14H20O10 Molecular Weight: 348.303 |
COA:
Product name: 2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranose
CAS: 3947-62-4 M.F.: C14H20O10 M.W.: 348.303 Batch No: 20130314 Quantity:375g
Items | Standards | Results |
Appearance | White crystalline powder | Positive |
Solubility | Readily soluble in CHC3and insoluble in water | Positive |
NMR and MS | Should comply | Complies |
Identification | IR and TLC | Positive |
M.P. | 120 ℃ –125 ℃ | 122 ℃ –124 ℃ |
Specific rotation [α]20/D,(C = 1,in CHC3) | +30° to +32° | +31.4° |
Loss Weight On Dryness | Max. 0.5% | Complies |
TLC | One spot | Complies |
Residue On Ignition | Max. 0.5% | Complies |
Assay (HPLC) | Min. 98% | 98.5% |
References:
1. Sambaiaha T, Fanwick PE, Cushman M, Synthesis 2001, p1450-1452
2. Sofian A, Lee C, J. Carbohydr. Chem. 2001, Vol20, Pt6, p431-440
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