144110-42-9 ,5-Bromo-6-chloro-3-indolyl b-D-glucuronide, CAS:144110-42-9

Cas:144110-42-9 ,
5-Bromo-6-chloro-3-indolyl b-D-glucuronide,
CAS:144110-42-9
C14H13BrClNO7 / 422.61
MFCD01311740

5-Bromo-6-chloro-3-indolyl b-D-glucuronide

5-溴-6-氯-3-吲哚-beta-D-葡萄糖醛酸苷

5-Bromo-6-chloro-3-indolyl b-D-glucuronide (5BCIG) is an antibiotic that inhibits bacterial growth by binding to the DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. 5BCIG is detectable in tissues, and quantified in blood. It encodes a protein to the cell cytoplasm. The sensitivity of 5BCIG against clostridium perfringens was found to be 10 times higher than that of penicillin G or erythromycin. 5BCIG has optimal activity against clostridium perfringens when expressed functionally as a polypeptide.

CAS Number	144110-42-9
Product Name	5-Bromo-6-chloro-3-indolyl-b-D-glucuronide
IUPAC Name	(2S,3S,4S,5R,6S)-6-[(5-bromo-6-chloro-1H-indol-3-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
Molecular Formula	C14H13BrClNO7
Molecular Weight	422.61 g/mol
InChI	InChI=1S/C14H13BrClNO7/c15-5-1-4-7(2-6(5)16)17-3-8(4)23-14-11(20)9(18)10(19)12(24-14)13(21)22/h1-3,9-12,14,17-20H,(H,21,22)/t9-,10-,11+,12-,14+/m0/s1
InChI Key	GAZVSOQUFLIBJQ-BYNIDDHOSA-N
SMILES	C1=C2C(=CC(=C1Br)Cl)NC=C2OC3C(C(C(C(O3)C(=O)O)O)O)O
Canonical SMILES	C1=C2C(=CC(=C1Br)Cl)NC=C2OC3C(C(C(C(O3)C(=O)O)O)O)O
Isomeric SMILES	C1=C2C(=CC(=C1Br)Cl)NC=C2O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(=O)O)O)O)O

CAS No: 144110-42-9 Synonyms: 5-Bromo-6-chloro-3-indolyl-b-D-glucopyranosiduronic acidMagenta GlcA MDL No: MFCD01311740 Chemical Formula: C14H13BrClNO7 Molecular Weight: 422.61

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