129787-66-2 ,Fluorescein di-b-D-glucopyranoside, FDGlu, CAS:129787-66-2

129787-66-2 ,Fluorescein di-b-D-glucopyranoside,FDGlu,
CAS:129787-66-2
C32H32O15 / 656.59
MFCD00133328

荧光素二(beta-D-吡喃葡萄糖苷), FDGlu, Fluorescein di-b-D-glucopyranoside

Fluorescein di-b-D-glucopyranoside is a fluorescent probe that binds to the glucosylceramide receptor. The in vitro assays showed that it inhibits amide hydrolase and fatty acid amide hydrolase activities. Fluorescein di-b-D-glucopyranoside can also inhibit the enzyme activity of gamma-aminobutyric acid (GABA) transaminase and oxadiazole synthase. This compound is a selective inhibitor of CB2 receptor, which is expressed in primary cells and has been shown to be involved in inflammatory responses.

Fluorescein Di-(β-D-glucopyranoside) is an ultrasensitive fluorogenic substrate for measurement of β-glucosidase activity in vivo or in vitro.

CAS Number	129787-66-2
Product Name	3',6'-Bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
IUPAC Name	3',6'-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]spiro[2-benzofuran-3,9'-xanthene]-1-one
Molecular Formula	C32H32O15
Molecular Weight	656.6 g/mol
InChI	InChI=1S/C32H32O15/c33-11-21-23(35)25(37)27(39)30(45-21)42-13-5-7-17-19(9-13)44-20-10-14(43-31-28(40)26(38)24(36)22(12-34)46-31)6-8-18(20)32(17)16-4-2-1-3-15(16)29(41)47-32/h1-10,21-28,30-31,33-40H,11-12H2/t21-,22-,23-,24-,25+,26+,27-,28-,30-,31-/m1/s1
InChI Key	ZTOBILYWTYHOJB-LWXMCBIJSA-N
SMILES	C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)OC5C(C(C(C(O5)CO)O)O)O)OC6=C3C=CC(=C6)OC7C(C(C(C(O7)CO)O)O)O
Canonical SMILES	C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)OC5C(C(C(C(O5)CO)O)O)O)OC6=C3C=CC(=C6)OC7C(C(C(C(O7)CO)O)O)O
Isomeric SMILES	C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)OC6=C3C=CC(=C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O

CAS No: 129787-66-2 Synonyms: FDGlu MDL No: MFCD00133328 Chemical Formula: C32H32O15 Molecular Weight: 656.59	In Stock.
References: 1. Kohen E, Kohen C, Hirschberg JG, Santus R, Grabowski G, Mangel W, Gatt S, Prince J,, Cell Biochem. Funct., 1993, 11, p167

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