87764-46-3 , 3-氟代-D-甘露糖, 3-fluoro-D-mannose,3DFM, CAS:87764-46-3

87764-46-3 , 3-氟代-D-甘露糖,
3-fluoro-D-mannose,
CAS:87764-46-3
C6H11FO5 / 182.15
MFCD00077530

3-氟代-D-甘露糖, 3-fluoro-D-mannose

3-Deoxy-3-fluoro-D-mannose (3DFM) is a synthetic sugar molecule that acts as an inhibitor of bacterial growth. It binds to the 6-phosphate group of nucleic acids, which prevents the addition of sugar molecules to ribose or deoxyribose groups. 3DFM also inhibits the synthesis of proteins and RNA, which are necessary for bacterial growth. 3DFM is a structural analog of mannose and glucose, and has been shown to be effective against chronic infections caused by bacteria that produce lectins, such as C. difficile. This drug can be used in combination with other antibiotics to enhance their effectiveness.

CAS Number	87764-46-3
Product Name	3-Deoxy-3-fluoro-D-mannose
IUPAC Name	(2R,3S,4R,5R)-3-fluoro-2,4,5,6-tetrahydroxyhexanal
Molecular Formula	C6H11FO5
Molecular Weight	182.147
InChI	InChI=1S/C6H11FO5/c7-5(3(10)1-8)6(12)4(11)2-9/h1,3-6,9-12H,2H2/t3-,4-,5-,6-/m1/s1
InChI Key	RMHCJIQOFXULDL-KVTDHHQDSA-N
SMILES	C(C(C(C(C(C=O)O)F)O)O)O

CAS No: 87764-46-3 MDL No: MFCD00077530 Chemical Formula: C6H11FO5 Molecular Weight: 182.15

References: 1. Biochem. J. 1983, 209 (3), p677-685

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