N-Nonanoyl-N-methylglucamine

N-壬酰基-N-甲基葡萄糖胺

N-Nonanoyl-N-methylglucamine is a nonionic surfactant that has been shown to be effective in the treatment of some inherited blood disorders. N-Nonanoyl-N-methylglucamine is used as a red cell membrane stabilizer and has been shown to increase the proton concentration in human serum. It also increases the transfer rate of p-nitrophenyl phosphate from erythrocytes to plasma. This drug has been found to have enzyme activity on soybean trypsin, model system, and epoxidase activity. N-Nonanoyl-N-methylglucamine has shown to be an effective protective agent against sodium citrate induced hemolysis and monoclonal antibody mediated cytotoxicity. It also shows kinetic data for protein synthesis and gene expression at different concentrations.

MEGA-9 is a nonionic detergent that can be used to solubilize membrane proteins. It has a critical micelle concentration (CMC) of 20 mM under no-salt conditions and CMCs ranging from 2 to 17.1 mM under high and low salt conditions for a variety of salts. It has been used to solubilize the melibiose transport carrier from E. coli membranes and reconstitute it into liposomes.

MEGA-9 (N-nonanoyl-N-methyl-D-glucamine) is a nonionic sugar-based surfactant. It is a membrane solubilizer and can forms vesicles.

Acyl-N-methylglucamide (MEGA) detergents are non-ionic detergents that provide a good starting point for your structural biology work. The hydrophilic head groups offer ample strength to extract proteins while still providing the capability to stabilize proteins in solution and promote crystal growth.

MEGA-9 is a nonionic detergent that can be used to solubilize membrane proteins.