83058-38-2 , D-十七乙酰基纤维五糖,
D-Cellopentose heptadecaacetate,
Cas:83058-38-2
C64H86O43 / 1543.34
MFCD01863365
D-十七乙酰基纤维五糖,
D-Cellopentose heptadecaacetate is a fluorinated, monosaccharide that is synthesized from the sugar cellobiose. It is an oligosaccharide and a complex carbohydrate with one of its glycosidic bonds modified by methylation. D-Cellopentose heptadecaacetate has been shown to be effective in inhibiting glycosylation reactions and can be used as a sugar substitute or for custom synthesis.
D-Cellopentose Heptadecaacetate (CPHA) is a carbohydrate derivative that has been widely studied due to its potential applications in various fields of research and industry. In this paper, we will explore the Definition and background of CPHA, Physical and Chemical Properties, Synthesis and Characterization, Analytical Methods, Biological Properties, Toxicity and Safety in Scientific Experiments, Applications in Scientific Experiments, Current State of Research, Potential Implications in Various Fields of Research and Industry, Limitations, and Future Directions.
Definition and background
D-Cellopentose Heptadecaacetate (CPHA) is a carbohydrate derivative that was first synthesized in 1969 by H. Klenk. CPHA is a structurally complex molecule composed of five sugar units linked together by glycosidic bonds and esterified with seven acetyl groups. The structure of CPHA makes it highly hydrophobic, making it difficult to dissolve in aqueous solutions.
Synthesis and Characterization
CPHA can be synthesized using different chemical methods. One of the most common methods involves the reaction between D-xylose and acetic anhydride to form a pentadecaacetate derivative, which is then converted to CPHA using hydrochloric acid. The resulting product is then purified using column chromatography and characterized using nuclear magnetic resonance (NMR) spectroscopy and high-performance liquid chromatography (HPLC).
Analytical Methods
Various analytical methods can be used to determine the purity and identity of CPHA. These methods include NMR spectroscopy, HPLC, mass spectrometry (MS), and infrared spectroscopy (IR).
Biological Properties
CPHA has been shown to exhibit various biological activities. Studies have demonstrated that CPHA has antifungal, antimicrobial, and antitumor properties. Additionally, CPHA has been found to have immunomodulatory effects, making it a potential candidate for the treatment of autoimmune diseases.
Toxicity and Safety in Scientific Experiments
Studies have shown that CPHA is relatively safe and non-toxic. However, the toxicity and safety of CPHA in humans have not been well established, and further studies are needed to determine its toxicity and safety in humans.
Applications in Scientific Experiments
CPHA has potential applications in various fields of research and industry, including as a drug delivery agent, antimicrobial agent, and anti-inflammatory agent. Its unique properties, including its hydrophobicity and stability, make it a promising candidate for these applications.
Current State of Research
Research on CPHA is ongoing, and studies continue to investigate its various properties and potential applications. Recent research has focused on the synthesis and characterization of CPHA derivatives and the use of CPHA as a drug delivery agent.
Potential Implications in Various Fields of Research and Industry
CPHA has potential applications in various fields of research and industry, including pharmaceuticals, biotechnology, and materials science. Its unique properties make it a promising candidate for drug delivery and other biomedical applications.
Limitations
Despite its potential applications, CPHA has some limitations. Its hydrophobicity and poor water solubility make it challenging to use in some applications, and additional research is needed to develop more efficient methods of synthesizing and utilizing CPHA.
Future Directions
There are several future directions for research on CPHA. These include developing more efficient synthesis methods, investigating its potential applications as a drug delivery agent, and exploring its immunomodulatory effects further. Additionally, research is needed to determine the toxicity and safety of CPHA in humans and establish its potential for use in the treatment of autoimmune diseases and other medical conditions.
CAS Number | 83058-38-2 |
Product Name | D-Cellopentose Heptadecaacetate |
IUPAC Name | [(2R,3R,4S,5R,6S)-4,5-diacetyloxy-3-[(2S,3R,4S,5R,6R)-3,4-diacetyloxy-6-(acetyloxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-[(2R,3R,4S,5R,6S)-4,5-diacetyloxy-2-(acetyloxymethyl)-6-[(2R,3R,4S,5R)-4,5,6-triacetyloxy-2-(acetyloxymethyl)oxan-3-yl]oxyoxan-3-yl]oxyoxan-2-yl]methyl acetate |
Molecular Formula | C64H86O43 |
Molecular Weight | 1543.34 |
InChI | InChI=1S/C64H86O43/c1-23(65)82-18-40-45(87-28(6)70)50(88-29(7)71)56(94-35(13)77)61(100-40)105-47-42(20-84-25(3)67)102-63(58(96-37(15)79)52(47)90-31(9)73)107-49-44(22-86-27(5)69)103-64(59(97-38(16)80)54(49)92-33(11)75)106-48-43(21-85-26(4)68)101-62(57(95-36(14)78)53(48)91-32(10)74)104-46-41(19-83-24(2)66)99-60(98-39(17)81)55(93-34(12)76)51(46)89-30(8)72/h40-64H,18-22H2,1-17H3/t40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50+,51+,52+,53+,54+,55-,56-,57-,58-,59-,60?,61+,62+,63+,64+/m1/s1 |
InChI Key | UTUMCHTVRXZKAE-VTHYYUHUSA-N |
SMILES | CC(=O)OCC1C(C(C(C(O1)OC2C(OC(C(C2OC(=O)C)OC(=O)C)OC3C(OC(C(C3OC(=O)C)OC(=O)C)OC(=O)C)COC(=O)C)COC(=O)C)OC(=O)C)OC(=O)C)OC4C(C(C(C(O4)COC(=O)C)OC5C(C(C(C(O5)COC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C |
Synonyms | O-2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl-(1-4)-O-2,3,6-tri-O-acetyl-β-D-glucopyranosyl-(1-4)-O-2,3,6-tri-O-acetyl-β-D-glucopyranosyl-(1-4)-O-2,3,6-tri-O-acetyl-β-D-glucopyranosyl-(1-4)-D-glucopyranose Tetraacetate; |
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