78341-33-0 ,异丙基-2-乙酰氨基-2-脱氧-beta-D-吡喃葡萄糖苷,
Isopropyl 2-acetamido-2-deoxy-b-D-glucopyranoside,
CAS:78341-33-0
C11H21NO6 / 263.29
MFCD08703886
异丙基-2-乙酰氨基-2-脱氧-beta-D-吡喃葡萄糖苷
Isopropyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a chromatographic agent used in liquid chromatography. It is a reaction product of polysaccharides and fatty acids, which are extracted from fruits. Isopropyl 2-acetamido-2-deoxy-b-D-glucopyranoside has been shown to inhibit the growth of typhimurium and other viruses in cell culture. The safety profile of this compound has not been established in humans and should be tested before use in vivo.
Isopropyl 2-acetamido-2-deoxy-b-D-glucopyranoside (IAG) is a chemical compound with various applications in scientific experiments. It is a derivative of N-acetylglucosamine and is frequently used in the fields of biochemistry, immunology, and biotechnology. This paper aims to provide an overview of IAG, its physical and chemical properties, synthesis and characterization, analytical methods, biological properties, toxicity and safety in scientific experiments, applications in scientific experiments, current state of research, potential implications in various fields of research and industry, limitations and future directions.
Definition and Background
IAG is a monosaccharide that is derived from N-acetylglucosamine. It is commonly used as a bioactive molecule in experiments related to cell-surface interactions, bacterial adhesion, and carbohydrate-protein recognition. IAG is also used as an intermediate in the synthesis of oligosaccharides and glycopeptides.
Physical and Chemical Properties
IAG is a white, crystalline powder that is sparingly soluble in water. It has a melting point of 192-194°C and a chemical formula of C11H21NO6. Its molecular weight is 263.29 g/mol.
Synthesis and Characterization
IAG can be synthesized using various methods. One common method is the reaction between N-acetylglucosamine and isopropylamine in the presence of acetic anhydride. The resulting product is purified through recrystallization and characterized using various analytical techniques such as nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry.
Analytical Methods
IAG can be analyzed using various techniques such as NMR spectroscopy, mass spectrometry, infrared spectroscopy, and high-performance liquid chromatography (HPLC). These techniques are used to determine the purity and characterization of IAG.
Biological Properties
IAG has various biological properties, including its ability to inhibit bacterial adhesion and biofilm formation. It also has potential therapeutic applications in the treatment of bacterial infections and cancer.
Toxicity and Safety in Scientific Experiments
IAG has low toxicity and is generally considered safe for use in scientific experiments. However, precautions should be taken when handling IAG, as it can be an irritant to skin and eyes.
Applications in Scientific Experiments
IAG has various applications in scientific experiments, including its use as a bioactive molecule in cell-surface interactions, bacterial adhesion, and carbohydrate-protein recognition. It is also used as an intermediate in the synthesis of oligosaccharides and glycopeptides.
Current State of Research
There is ongoing research on the potential therapeutic applications of IAG in the treatment of bacterial infections and cancer. Additionally, research is being conducted on the synthesis of new derivatives of IAG with improved biological properties.
Potential Implications in Various Fields of Research and Industry
IAG has potential implications in various fields of research and industry, including biotechnology, pharmacology, and medical research. Its ability to inhibit bacterial adhesion and biofilm formation makes it a potential candidate for the development of new antibiotics and anti-biofilm agents.
Limitations and Future Directions
One limitation of IAG is its limited solubility in water, which makes it difficult to use in certain experiments. Future research should focus on developing new derivatives of IAG with improved solubility and biological properties. Additionally, research is needed to further explore the potential therapeutic applications of IAG in the treatment of bacterial infections and cancer.
Conclusion
In conclusion, Isopropyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a chemical compound with various applications in scientific experiments. It has physical and chemical properties that make it an ideal candidate for numerous experiments. Its potential therapeutic applications in the treatment of bacterial infections and cancer make it an exciting area of ongoing research. Although there are some limitations associated with the use of IAG, the future directions for research into this chemical compound are numerous and exciting.
CAS Number | 78341-33-0 |
Product Name | Isopropyl 2-acetamido-2-deoxy-b-D-glucopyranoside |
IUPAC Name | (2R,3S,4R,5R,6S)-5-amino-6-[(2R,4R,5R)-5-amino-6-[(2R,3S,4R,5R,6R)-5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-2-(hydroxymethyl)oxane-3,4-diol |
Molecular Formula | C11H21NO6 / 263.29 |
Molecular Weight | 263.29 g/mol |
InChI | InChI=1S/C18H35N3O13/c19-7-12(27)14(5(2-23)30-16(7)29)33-18-9(21)13(28)15(6(3-24)32-18)34-17-8(20)11(26)10(25)4(1-22)31-17/h4-18,22-29H,1-3,19-21H2/t4-,5-,6-,7-,8-,9-,10-,11-,12-,13-,14-,15?,16-,17+,18?/m1/s1 |
InChI Key | RQFQJYYMBWVMQG-KAPKVSAKSA-N |
SMILES | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)N)OC3C(OC(C(C3O)N)O)CO)CO)N)O)O)O |
Canonical SMILES | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)N)OC3C(OC(C(C3O)N)O)CO)CO)N)O)O)O |
Isomeric SMILES | C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)OC2[C@H](OC([C@@H]([C@H]2O)N)O[C@@H]3[C@H](O[C@H]([C@@H]([C@H]3O)N)O)CO)CO)N)O)O)O |
CAS No: 78341-33-0 MDL No: MFCD08703886 Chemical Formula: C11H21NO6 Molecular Weight: 263.29 |
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