Acetyl coenzyme A trilithium salt trihydrate;Acetyl CoALi3 . 3H2O

Acetyl-CoA, also known as acetyl coenzyme A or accoa, belongs to the class of organic compounds known as acyl coas. These are organic compounds containing a coenzyme A substructure linked to an acyl chain. Thus, acetyl-CoA is considered to be a fatty ester lipid molecule. Acetyl-CoA is slightly soluble (in water) and an extremely strong acidic compound (based on its pKa). Acetyl-CoA has been found throughout most human tissues, and has also been primarily detected in urine. Acetyl-CoA can be found anywhere throughout the human cell, such as in mitochondria, cytoplasm, golgi, and endoplasmic reticulum. Acetyl-CoA exists in all eukaryotes, ranging from yeast to humans. Acetyl-CoA and glucosamine 6-phosphate can be converted into N-acetyl-D-glucosamine 6-phosphate; which is mediated by the enzyme glucosamine 6-phosphate N-acetyltransferase. In humans, acetyl-CoA is involved in the lovastatin action pathway, the Beta-alanine metabolism pathway, the oxidation OF branched chain fatty acids pathway, and the citric Acid cycle pathway. Acetyl-CoA is also involved in several metabolic disorders, some of which include 4-hydroxybutyric aciduria/succinic semialdehyde dehydrogenase deficiency, the NON ketotic hyperglycinemia pathway, pyruvate dehydrogenase deficiency (e2), and the primary hyperoxaluria II, PH2 pathway.

Acetyl-CoA is an acyl-CoA having acetyl as its S-acetyl component. It has a role as an effector, a coenzyme, an acyl donor and a fundamental metabolite. It derives from an acetic acid and a coenzyme A. It is a conjugate acid of an acetyl-CoA(4-).

Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.