66642-36-2 , L-Pyroglutamic acid-AMC ; L-Pyroglutamic acid 7-amido-4-methylcoumarin

66642-36-2 , L-Pyroglutamic acid-AMC ;
L-Pyroglutamic acid 7-amido-4-methylcoumarin
C15H14N2O4 / 286.28
MFCD00080240

L-Pyroglutamic acid-AMC

L-Pyroglutamic acid 7-amido-4-methylcoumarin

L-Pyroglutamic acid 7-amido-4-methylcoumarin (L-PGAMC) is a chromogenic substrate that can be used in the detection of ligands. L-PGAMC reacts with a wide variety of ligands, including metal ions and cofactors, which are vital to many cellular processes. L-PGAMC can also be used in the diagnosis of diseases such as cancer, diabetes, and Alzheimer's disease.

CAS Number	66642-36-2
Product Name	L-Pyroglutamic acid 7-amido-4-methylcoumarin
IUPAC Name	N-(4-methyl-2-oxochromen-7-yl)-5-oxopyrrolidine-2-carboxamide
Molecular Formula	C15H14N2O4
Molecular Weight	286,29 g/mole
InChI	InChI=1S/C15H14N2O4/c1-8-6-14(19)21-12-7-9(2-3-10(8)12)16-15(20)11-4-5-13(18)17-11/h2-3,6-7,11H,4-5H2,1H3,(H,16,20)(H,17,18)
InChI Key	GMVNXBGNKSQHIT-NSHDSACASA-N
SMILES	CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C3CCC(=O)N3
Synonyms	L-Pyroglutamicacid7-amido-4-methylcoumarin;66642-36-2;ST50307661;(2S)-N-(4-methyl-2-oxochromen-7-yl)-5-oxopyrrolidine-2-carboxamide;Pyr-AMC;pGlu-Aminomethylcoumarin;AC1MBZP6;N9890_FLUKA;N9890_SIGMA;33899_RIEDEL;33899_FLUKA;MolPort-003-930-459;ZINC391922;7342AH;AKOS024306956;NCGC00185759-01;AM030354;HE005986;FT-0628009;L-Pyroglutamicacid4-methyl-7-coumarinylamide;P-8500;3B3-054409;L-PYROGLUTAMICACID4-METHYL-7-COUMARINYLAMIDEHYDRATE;((2S)-5-oxopyrrolidin-2-yl)-N-(4-methyl-2-oxochromen-7-yl)carboxamide;(2S)-N-(4-methyl-2-oxo-2H-chromen-7-yl)-5-oxopyrrolidine-2-carboxamide
Canonical SMILES	CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C3CCC(=O)N3
Isomeric SMILES	CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@@H]3CCC(=O)N3