6205-69-2 ,2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosyl azide,
CAS: 6205-69-2
C14H20N4O8 / 372.33
MFCD00216968
2-乙酰氨基-三-O-乙酰基-2-脱氧-β-D-叠氮基吡喃葡萄糖苷,
2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-beta-D-glucopyranosyl azide (ATAG) is a chemical compound with extensive research as an azide derivative of a saccharide molecule. In this paper, we will discuss the properties, synthesis, analytical methods, biological properties, toxicity and safety, applications, current state of research, potential implications, limitations, and future directions of 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-beta-D-glucopyranosyl azide.
Definition and background:
ATAG is a derivative of a saccharide molecule, which can be obtained with the reaction of the saccharide with azido acetyl compounds. It is a white crystalline powder that has been extensively studied for its potential applications in various biological and chemical fields.
Synthesis and Characterization:
ATAG can be synthesized by using various azido acetyl compounds. The reaction of saccharide with azido acetyl compounds leads to the formation of ATAG. The synthesized ATAG can be characterized through various techniques, including NMR spectroscopy, Mass spectrometry, and FTIR spectroscopy.
Analytical Methods:
High-performance liquid chromatography (HPLC) is one of the most commonly used analytical methods for the detection of ATAG. It has also been analyzed through mass spectrometry.
Biological Properties:
Several studies suggest that ATAG has significant anti-tumor and anti-viral properties. Its anti-tumor effect is due to its ability to inhibit cell proliferation, induce apoptosis, and inhibit angiogenesis. Moreover, ATAG has shown potent anti-viral activity against both RNA and DNA viruses.
Toxicity and Safety in Scientific Experiments:
Most of the studies conducted on ATAG have not reported any significant toxicity or safety issues. However, some studies suggest the potential toxicity of ATAG when used in higher concentrations. Therefore, it is recommended to use ATAG in lower concentrations and perform toxicity tests before using it in experiments.
Applications in Scientific Experiments:
ATAG has various applications in scientific experiments, including the synthesis of various molecules, covalent labeling, and bioconjugation. It has also been used extensively in click chemistry and as a linker in drug design.
Current State of Research:
Current research on ATAG mainly focuses on its applications in the areas of chemical biology and chemotherapy. Moreover, various studies have also been conducted on the effect of ATAG on different biological systems.
Potential Implications in Various Fields of Research and Industry:
ATAG has a wide range of potential implications in various fields, including chemical biology, drug design, and biomedical research. Its potential use as an anti-tumor and anti-viral agent makes it a promising candidate for further research in these areas.
Limitations and Future Directions:
Despite its extensive research, there are still several limitations to the use of ATAG in various applications. Therefore, future research should focus on addressing these limitations, including enhancing its stability in different conditions and reducing its potential toxicity. Moreover, further research is also needed to explore its potential applications in different fields.
Future Directions:
Several future directions can be explored in the research on ATAG. These include:
1) Developing new methods for the synthesis of ATAG with higher yields.
2) Investigating its potential as a diagnostic agent in various diseases.
3) Exploring the possibility of its use in targeted drug delivery.
4) Developing new analytical methods for the detection of ATAG.
5) Studying its potential use as a biomarker for various diseases.
In conclusion, ATAG is a promising candidate with many potential applications in different fields. Its wide range of biological activities makes it a promising compound for future research in various scientific disciplines. However, more research is needed to understand its full potential and address its limitations.
CAS Number | 6205-69-2 |
Product Name | 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-beta-D-glucopyranosyl Azide |
IUPAC Name | [(2R,3S,4R,5R,6R)-5-acetamido-3,4-diacetyloxy-6-azidooxan-2-yl]methyl acetate |
Molecular Formula | C14H20N4O8 |
Molecular Weight | 372.33 g/mol |
InChI | InChI=1S/C14H20N4O8/c1-6(19)16-11-13(25-9(4)22)12(24-8(3)21)10(5-23-7(2)20)26-14(11)17-18-15/h10-14H,5H2,1-4H3,(H,16,19)/t10-,11-,12-,13-,14-/m1/s1 |
InChI Key | RMCFMPMNMQZHSF-DHGKCCLASA-N |
SMILES | CC(=O)NC1C(C(C(OC1N=[N+]=[N-])COC(=O)C)OC(=O)C)OC(=O)C |
Synonyms | 2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosyl Azide; |
Canonical SMILES | CC(=O)NC1C(C(C(OC1N=[N+]=[N-])COC(=O)C)OC(=O)C)OC(=O)C |
Isomeric SMILES | CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1N=[N+]=[N-])COC(=O)C)OC(=O)C)OC(=O)C |
COA:
Product name: 2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-beta-D-glucopyranosyl azide
M.F.:C14H20N4O8 M.W.: 372.33 CAS: 6205-69-2
Items | Standards | Results |
Appearance | White crystal powder | Complies |
Solubility | Easily soluble in EtOAc, insoluble in water | Complies |
Identification | IR and HPLC | Complies |
Melting point | 163°C -166°C | 164℃ -166℃ |
Loss weight on drying | Max. 0.5% | 0.2% |
Residue on ignition | Max. 0.5% | 0.1% |
TLC | Should be one spot | one spot |
Assay | Min. 98% | 98.2% |
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