54010-71-8, D-葡萄糖-6-磷酸单钠盐, Robison Ester Monosodium Salt, CAS:54010-71-8

54010-71-8, D-Glucose-6-phosphate monosodium salt ,
CAS:54010-71-8
C6H12NaO9P / 282.12
MFCD00136039

D-葡萄糖-6-磷酸单钠盐,D-Glucose-6-phosphate monosodium salt

D-Glucose-6-phosphate is formed in cells when glucose is phosphorylated by hexokinase (or glucokinase) or by the conversion of glucose-1-phosphate by phosphoglucomutase, which is the first step of glycogen synthesis. It is stored as glycogen when blood glucose levels are high. Disruption of D-glucose-6-phosphate activity leads to glycogen storage disease type I or von Gierke’s disease, a group of inherited metabolic diseases characterized by severe hypoglycemia, growth retardation, and hepatomegaly, due to accumulation of glycogen and fat in the liver. D-Glucose-6-phosphate is also the starting molecule of both glycolysis and the pentose phosphate pathways. Because cancer cells adopt glycolysis as a major source of metabolic energy production, and the pentose phosphate pathway plays a role in helping glycolytic cancer cells to meet their anabolic demands, this compound can be used to study the progression of this process.

CAS No: 54010-71-8 Synonyms: Robison Ester Monosodium Salt MDL No: MFCD00136039 Chemical Formula: C6H12NaO9P Molecular Weight: 282.12

CAS Number	54010-71-8
Product Name	Sodium (2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl hydrogenphosphate
IUPAC Name	sodium;[(2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl] hydrogen phosphate
Molecular Formula	C6H12NaO9P
Molecular Weight	282.12 g/mol
InChI	InChI=1S/C6H13O9P.Na/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14;/h1,3-6,8-11H,2H2,(H2,12,13,14);/q;+1/p-1/t3-,4+,5+,6+;/m0./s1
InChI Key	OBHLNVXMRZXIII-BTVCFUMJSA-M
SMILES	C(C(C(C(C(C=O)O)O)O)O)OP(=O)(O)[O-].[Na+]
Synonyms	G6P;Sodium Glucose-6-Phosphate
Canonical SMILES	C(C(C(C(C(C=O)O)O)O)O)OP(=O)(O)[O-].[Na+]
Isomeric SMILES	C([C@H]([C@H]([C@@H]([C@H](C=O)O)O)O)O)OP(=O)(O)[O-].[Na+]

COA:

Product name: D-Glucose-6-phosphate monosodium salt CAS: 54010-71-8

M.F.: C₆H₁₂NaO₈P M.W._:282.12 Batch No: 20121101 Quantity: 17.5g

*Items*	*Standards*	*Results*
Appearance	White crystal powder	Complies
Solubility	Easily soluble in water, insoluble in ether	Complies
Identification	IR	Complies
NMR and MS	Should comply	Comply
Specific rotation ( [α]^20/D, in H₂O)	+31^o ~ +35^o	32.5^o
Any other impurity	Max. 1%	Complies
Water content (Karl Fischer)	Max. 1%	0.23%
P inorganic	Max. 0.5%	Complies
Assay	Min. 98%	98.6%