4990-81-2 , 6-氯-D-甘露糖,
6-Chloro-D-mannose,
CAS:4990-81-2
C6H11ClO5 / 198.60
MFCD00671701
6-Chloro-6-deoxy-D-mannose
CAS No: 4990-81-2 MDL No: MFCD00671701 Chemical Formula: C6H11ClO5 Molecular Weight: 198.60 |
6-Chloro-6-deoxy-D-mannose is a naturally occurring sugar that is found in the spermatozoa of many animals. It is a mannose derivative that has been shown to be an inhibitor of the enzyme glyceraldehyde 3-phosphate dehydrogenase, which plays an important role in energy metabolism and isomerization of 6-phosphate to glucose-1 phosphate. This property may be responsible for its contraceptive effects. The drug also inhibits phosphoglucomutase and enhances the transfer of glucose from the liver to other tissues, increasing blood glucose concentrations. 6-Chloro-6 deoxy mannose also has antifertility effects in rats by inhibiting transfer of spermatozoa through the female reproductive tract.
CAS Number | 4990-81-2 |
Product Name | (2S,3S,4S,5S)-6-Chloro-2,3,4,5-tetrahydroxyhexanal |
IUPAC Name | (2S,3S,4S,5S)-6-chloro-2,3,4,5-tetrahydroxyhexanal |
Molecular Formula | C6H11ClO5 |
Molecular Weight | 198.6 g/mol |
InChI | InChI=1S/C6H11ClO5/c7-1-3(9)5(11)6(12)4(10)2-8/h2-6,9-12H,1H2/t3-,4-,5-,6-/m1/s1 |
InChI Key | ZHVNVPHMOCWHHO-UHFFFAOYSA-N |
SMILES | C(C(C(C(C(C=O)O)O)O)O)Cl |
Synonyms | 6-chloro-6-deoxymannose |
Canonical SMILES | C(C(C(C(C(C=O)O)O)O)O)Cl |
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