480-10-4 , 山奈酚-3-O-b-D-葡萄糖苷,
Kaempferol 3-β-D-glucopyranoside,
CAS:480-10-4
C21H20O11 / 448.38
MFCD00075932
Kaempferol 3-b-glucopyranoside
Kaempferol 3-b-glucopyranoside is a flavonoid that belongs to the group of apigenin and kaempferol. It has been shown to inhibit free radical production, which can cause cell injury, by binding to the cell membrane in an antioxidant capacity. Kaempferol 3-b-glucopyranoside also has anti-inflammatory properties and has been shown to reduce inflammation in the kidneys. This compound may act on toll-like receptor 4 (TLR4) by binding to DNA response elements. Kaempferol 3-b-glucopyranoside also inhibits the Bcl-2 protein, which is involved in apoptosis.
Kaempferol-3-O-glucoside analytical standard provided with w/w absolute assay, to be used for quantitative titration.
Kaempferol 3-glucoside is a flavonoid glycoside that occurs naturally in Cleome and Capparis species of plants.
Astragalin belongs to the class of organic compounds known as flavonoid-3-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C3-position. Astragalin exists as a solid, slightly soluble (in water), and a very weakly acidic compound (based on its pKa). Within the cell, astragalin is primarily located in the cytoplasm. Astragalin can be converted into astragalin heptaacetate and 2''-acetylastragalin. Outside of the human body, astragalin can be found in a number of food items such as tamarind, american cranberry, chickpea, and bilberry. This makes astragalin a potential biomarker for the consumption of these food products.
Kaempferol 3-O-beta-D-glucoside is a kaempferol O-glucoside in which a glucosyl residue is attached at position 3 of kaempferol via a beta-glycosidic linkage. It has a role as a trypanocidal drug and a plant metabolite. It is a kaempferol O-glucoside, a monosaccharide derivative, a trihydroxyflavone and a beta-D-glucoside.
CAS Number | 480-10-4 |
Product Name | Astragalin |
IUPAC Name | 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one |
Molecular Formula | C21H20O11 |
Molecular Weight | 448.38 g/mol |
InChI | InChI=1S/C21H20O11/c22-7-13-15(26)17(28)18(29)21(31-13)32-20-16(27)14-11(25)5-10(24)6-12(14)30-19(20)8-1-3-9(23)4-2-8/h1-6,13,15,17-18,21-26,28-29H,7H2/t13-,15-,17+,18-,21+/m1/s1 |
InChI Key | JPUKWEQWGBDDQB-QSOFNFLRSA-N |
SMILES | O=C1C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)=C(C3=CC=C(O)C=C3)OC4=CC(O)=CC(O)=C14 |
Solubility | Soluble in DMSO |
Synonyms | Astragalin; Astragaline; K5; Kaempferol-3-beta-glucopyranoside; Kaempferol-3-beta-monoglucoside; Kaempferol-3-glucoside; Kaempferol-3-O-glucoside; UNII-APM8UQ3Z9O; |
Canonical SMILES | C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O |
Isomeric SMILES | C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O |
CAS No: 480-10-4 Synonyms: Astragaline3,4',5,7-Tetrahydroxyflavone-3-glucoside MDL No: MFCD00075932 Chemical Formula: C21H20O11 Molecular Weight: 448.38 |
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