4163-44-4 , Tetra-O-acetyl-a-D-galactopyranosyl fluoride,
四乙酰基-α-D-氟代半乳糖,
CAS: 4163-44-4
C14H19O9F / 350.29
MFCD00792704
四乙酰基-α-D-氟代半乳糖,
2,3,4,6-tetra-o-acetyl-alpha-D-galactopyranosyl fluoride is a white crystalline substance that is used in numerous scientific experiments. It is classified as a glycosyl fluoride derivative and is a popular intermediate in organic synthesis. Additionally, it can be used in drug design, chemical biology, and carbohydrate research.
Synthesis and Characterization:
2,3,4,6-tetra-o-acetyl-alpha-D-galactopyranosyl fluoride can be synthesized by acetylation of alpha-D-galactopyranosyl fluoride with acetic anhydride in the presence of a small amount of concentrated sulfuric acid. Proton and carbon spectroscopy are the most common analytical methods used to characterize glycosyl fluoride derivatives like 2,3,4,6-tetra-o-acetyl-alpha-D-galactopyranosyl fluoride.
Analytical Methods:
Analytical methods like nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, and high-performance liquid chromatography (HPLC) are extensively used to analyze 2,3,4,6-tetra-o-acetyl-alpha-D-galactopyranosyl fluoride.
Biological Properties:
2,3,4,6-tetra-o-acetyl-alpha-D-galactopyranosyl fluoride is known to exhibit antitumor, antiviral, and antibacterial properties. Its ability to inhibit enzymes involved in various cellular processes makes it a potential candidate for drug development.
Toxicity and Safety in Scientific Experiments:
While performing scientific experiments, it is important to take precautionary measures while handling 2,3,4,6-tetra-o-acetyl-alpha-D-galactopyranosyl fluoride. It may cause irritation to the eyes and respiratory tract, and must be handled in a well-ventilated area with appropriate protective gear.
Applications in Scientific Experiments:
2,3,4,6-tetra-o-acetyl-alpha-D-galactopyranosyl fluoride has wide applicability in the field of chemical biology, organic chemistry, and drug design. It is used in the synthesis of complex oligosaccharides, glycopeptides, and glycolipids.
Current State of Research:
There is continued research on the biological activity of 2,3,4,6-tetra-o-acetyl-alpha-D-galactopyranosyl fluoride as well as its applications in drug development. Further, its compound is under the constant exploration for its role in glycosylation-based immunotherapy.
Potential Implications in Various Fields of Research and Industry:
2,3,4,6-tetra-o-acetyl-alpha-D-galactopyranosyl fluoride has the potential for application in various fields such as medical research, disease diagnosis, and drug development.
Limitations and Future Directions:
Current advancements in the glycosylation field have demonstrated the need to evolve and develop new methods. Assessment of new synthesis techniques like enzymatic and chemoenzymatic approaches will provide a new area for 2,3,4,6-tetra-o-Acetyl-alpha-D-galactopyranosyl fluoride synthesis. Understanding of the influence of the stereochemistry of this molecule on its biological activity would be of immense interest.
Future Directions:
Future studies can focus on determining the potency of 2,3,4,6-tetra-o-Acetyl-alpha-D-galactopyranosyl fluoride in modulating carbohydrate-protein interactions. Analysis of its use in the development of vaccines or drugs for the prevention of infectious diseases should be evaluated. Besides, evaluating the role of 2,3,4,6-tetra-o-acetyl-alpha-D-galactopyranosyl fluoride in cancer immunotherapy and its effects on immunogenicity would also be beneficial. Finally, a study of its mechanism of action and potential side effects will be of enormous assistance in further research.
In conclusion, 2,3,4,6-tetra-o-acetyl-alpha-D-galactopyranosyl fluoride has broad applications in medical research and drug development that have yet to be fully explored. Further research is necessary to unlock its potential and opportunities for improved scientific understanding.
CAS Number | 4163-44-4 |
Product Name | 2,3,4,6-tetra-o-Acetyl-alpha-D-galactopyranosyl fluoride |
IUPAC Name | [(2R,3S,4S,5R,6R)-3,4,5-triacetyloxy-6-fluorooxan-2-yl]methyl acetate |
Molecular Formula | C14H19FO9 |
Molecular Weight | 350.29 g/mol |
InChI | InChI=1S/C14H19FO9/c1-6(16)20-5-10-11(21-7(2)17)12(22-8(3)18)13(14(15)24-10)23-9(4)19/h10-14H,5H2,1-4H3/t10-,11+,12+,13-,14+/m1/s1 |
InChI Key | JJXATNWYELAACC-HTOAHKCRSA-N |
SMILES | CC(=O)OCC1C(C(C(C(O1)F)OC(=O)C)OC(=O)C)OC(=O)C |
Canonical SMILES | CC(=O)OCC1C(C(C(C(O1)F)OC(=O)C)OC(=O)C)OC(=O)C |
Isomeric SMILES | CC(=O)OC[C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)F)OC(=O)C)OC(=O)C)OC(=O)C |
CAS No: 4163-44-4 Synonyms: Acetofluoro-a-D-galactose MDL No: MFCD00792704 Chemical Formula: C14H19O9F Molecular Weight: 350.29 | white crystalline powder. In Stock.现货 |
References: 1. Caddick S, Motherwell WB, Wilkinson JA,, J. Chem. Soc. Commun., 1991, p6742. Ernst B, Winkler T,, Tetrahedron Lett., 1989, 30, p30813. Szarek WA, Grynkiewicz G, Doboszewski B, Hay GW,, Chem. Lett., 1984, p1751 |
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