4148-71-4 , Methyl 2,3:4,6-di-O-benzylidene-a-D-mannopyranoside,
甲基-2,3:4,6-O-二苄叉-alpha-D-吡喃甘露糖苷,
CAS:4148-71-4
C21H22O6 / 370.4
MFCD00192286
甲基-2,3:4,6-O-二苄叉-alpha-D-吡喃甘露糖苷,
Methyl 2,3:4,6-di-O-benzylidene-a-D-mannopyranoside is a cyclic peptide that was developed for the treatment of tropical diseases. It has been shown to be a potent inhibitor of protein synthesis and an absorber of amino acids in experimental infections. Comparative studies have shown that this drug inhibits protein synthesis more than other cyclic peptides. Methyl 2,3:4,6-di-O-benzylidene-a-D-mannopyranoside has also been shown to have antiinflammatory properties in inflammatory bowel disease and may be useful as a therapeutic agent for Alzheimer’s disease or cancer.
CAS Number | 4148-71-4 |
Product Name | Methyl 2,3:4,6-di-O-benzylidene-alpha-D-mannopyranoside |
IUPAC Name | 7-methoxy-4,12-diphenyl-3,5,8,11,13-pentaoxatricyclo[7.4.0.02,6]tridecane |
Molecular Formula | C₂₁H₂₂O₆ |
Molecular Weight | 370.4 g/mol |
InChI | InChI=1S/C21H22O6/c1-22-21-18-17(26-20(27-18)14-10-6-3-7-11-14)16-15(24-21)12-23-19(25-16)13-8-4-2-5-9-13/h2-11,15-21H,12H2,1H3 |
InChI Key | VGLOFWHLPMVSBF-UHFFFAOYSA-N |
SMILES | COC1C2C(C3C(O1)COC(O3)C4=CC=CC=C4)OC(O2)C5=CC=CC=C5 |
Synonyms | Methyl 2,3:4,6-Bis-O-(phenylmethylene)-α-D-mannopyranoside; NSC 266498; |
Canonical SMILES | COC1C2C(C3C(O1)COC(O3)C4=CC=CC=C4)OC(O2)C5=CC=CC=C5 |
Isomeric SMILES | CO[C@@H]1[C@@H]2[C@H]([C@H]3[C@H](O1)COC(O3)C4=CC=CC=C4)OC(O2)C5=CC=CC=C5 |
CAS No: 4148-71-4,71484-87-2 MDL No: MFCD00192286 Chemical Formula: C21H22O6 Molecular Weight: 370.4 |
References: 1. Grishkovets VI, Zemlyakov AE, Chirva VY, Chem. Nat. Compd. 1983, Vol18, No1, p112-113 |
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