38440-79-8,2-脱氧-2-氟-D-甘露糖
2-Fluoro-2-deoxy-D-mannose
CAS: 38440-79-8
C6H11FO5 / 182.15
MFCD00797602
2-Deoxy-2-fluoro-D-mannose is known for its antiviral properties as a sugar analog and glycosylation inhibitor. It works by inhibiting the glycosylation of viral envelope proteins, which can prevent viral replication and reduce viral infectivity. Studies have shown that 2-deoxy-2-fluoro-D-mannose can inhibit the replication of various viruses, including influenza A virus, human immunodeficiency virus (HIV), and hepatitis C virus (HCV). Inhibition of viral glycosylation by 2-Deoxy-2-fluoro-D-mannose can also enhance the effectiveness of some antiviral drugs, making them more potent.
CAS No: 38440-79-8,31077-88-0 Product Code: MD03540 MDL No: MFCD00797602 Chemical Formula: C6H11FO5 Molecular Weight: 182.15 | |
COA: |
Items | Standards | Results |
Appearance | White or off-white power | Positive |
Solubility | Readily soluble in water and insoluble in ether | Positive |
NMR and MS | Should comply | Complies |
Identification | IR and TLC | Positive |
Loss Weight On Dryness | Max. 0.5% | Complies |
Residue on ignition | Max. 0.5% | Complies |
TLC (15%H2SO4-C2H5OH) | Should be one spot | One spot |
Assay TLC | Min. 95% | 98.2% |
References:
1. McDowell W, Datema R, Romero PA, Schwarz RT, Biochemistry 1985, 24, p8145-52
2. Haradahira T, Maeda M, Omae H, Yano Y, Kojima M, Chem. Pharm. Bull (Tokyo) 1984, Dec32(12), 4758-66
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