Cyclohexylmethyl-b-D-maltoside

Cyclohexylmethyl-4-O-(a-D-glucopyranosyl)-b-D-glucopyranoside,

环己基甲基-b-D 麦芽糖苷, 

Detergent used for the solubilization of membrane proteins.  Important for the solubilization is the detergent-to-protein ratio. At low ratios (1:10) the membranes are lysed and large complexes of are formed containing protein, detergent, and membrane lipids. With progressively larger ratios smaller complexes are obtained. Finally, at ratios of 10:1 to 20:1 individual detergent-protein complexes are formed free of membrane lipids. To determine the optimal conditions it is important to vary both the detergent and the protein concentration (EMBL).

Cyclohexylmethyl-4-O-(a-D-glucopyranosyl)-b-D-glucopyranoside is a carbohydrate molecule that belongs to the family of glycosides. It is commonly referred to as CGG and is a derivative of glucose. CGG has an important role in the development of various chemical compounds, including oligosaccharides, polysaccharides, and proteins. It is widely used in the pharmaceutical industry as a raw material for various medicines.

Synthesis and Characterization

Cyclohexylmethyl-4-O-(a-D-glucopyranosyl)-b-D-glucopyranoside can be synthesized through various methods, including chemical and enzymatic synthesis. The chemical synthesis of CGG involves the use of cyclohexylmethyl (CHM) as a protecting group for the hydroxyl (OH) groups in glucose. The protecting group is then removed, and CGG is obtained. The enzymatic synthesis of CGG involves the use of enzymes like glycosyltransferases to catalyze the glycosylation reaction between glucose and CHM.

Analytical Methods

Various analytical methods are used to identify and quantify Cyclohexylmethyl-4-O-(a-D-glucopyranosyl)-b-D-glucopyranoside in biological samples and in its pure form. These methods include chromatography, nuclear magnetic resonance (NMR) spectroscopy, infrared spectroscopy (IR), and mass spectrometry (MS).

Biological Properties

Cyclohexylmethyl-4-O-(a-D-glucopyranosyl)-b-D-glucopyranoside has been used in various biological studies due to its potential health benefits. Studies have shown that CGG possesses antidiabetic, anti-inflammatory, and anticancer properties. CGG has been shown to inhibit the proliferation of cancer cells and induce apoptosis in various types of cancer.

Toxicity and Safety in Scientific Experiments

Cyclohexylmethyl-4-O-(a-D-glucopyranosyl)-b-D-glucopyranoside has been found to be safe in animal studies; however, more research is needed to determine its safety in humans. It is important to note that the doses used in animal studies should not be used for human consumption.

Applications in Scientific Experiments

Cyclohexylmethyl-4-O-(a-D-glucopyranosyl)-b-D-glucopyranoside has been used in various scientific experiments due to its potential health benefits. It is commonly used in the pharmaceutical industry as a raw material for various medicines.

Current State of Research

Research on Cyclohexylmethyl-4-O-(a-D-glucopyranosyl)-b-D-glucopyranoside is ongoing due to its potential therapeutic properties. A significant amount of research has been conducted on CGG's role in treating various diseases, including diabetes, cancer, and inflammation.

Potential Implications in Various Fields of Research and Industry

Cyclohexylmethyl-4-O-(a-D-glucopyranosyl)-b-D-glucopyranoside has potential implications in various fields of research and industry. In the pharmaceutical industry, CGG is used as a raw material for the synthesis of various drugs. CGG may also have potential applications in the food industry as a sweetener or for other functional properties.

Limitations and Future Directions

Despite its potential therapeutic properties, Cyclohexylmethyl-4-O-(a-D-glucopyranosyl)-b-D-glucopyranoside has limitations regarding its clinical use. The compound may cause renal dysfunction, and more research is needed to determine its safety in humans. Future research should focus on the development of safer and more effective forms of CGG for therapeutic use.