143547-78-8 , 4-Trifluoromethylumbelliferyl b-D-glucuronide potassium salt

Cas:143547-78-8 ,
4-Trifluoromethylumbelliferyl b-D-glucuronide potassium salt
C16H12F3O9K / 444.35
MFCD00132981

4-Trifluoromethylumbelliferyl b-D-glucuronide potassium salt

4-Trifluoromethylumbelliferyl b-D-glucuronide potassium salt (4TUF) is a fluorogenic substrate used in enzyme and diagnostic research. It is a conjugate of the b-D-glucuronide moiety with 4-trifluoromethylumbelliferone. 4TUF exhibits high quality and purity, which makes it suitable for use in food testing, diagnostics, and other applications requiring high quality fluorogenic substrates. 4TUF can be used as a chromogenic substrate for the detection of glucuronidase activity in cells or tissue cultures. The enzyme hydrolyzes the ester bond between the b-D-glucuronide moiety and 4TUF to release the fluorescent compound 4-trifluoromethylumbelliferone. This product also has been shown to be an effective chemiluminescent substrate for horseradish peroxidase

CAS Number	143547-78-8
Product Name	4-Trifluoromethylumbelliferyl b-D-glucuronide potassium salt
IUPAC Name	potassium;(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-oxo-4-(trifluoromethyl)chromen-7-yl]oxyoxane-2-carboxylate
Molecular Formula	C₁₆H₁₂F₃KO₉
Molecular Weight	444.35
InChI	InChI=1S/C16H13F3O9.K/c17-16(18,19)7-4-9(20)27-8-3-5(1-2-6(7)8)26-15-12(23)10(21)11(22)13(28-15)14(24)25;/h1-4,10-13,15,21-23H,(H,24,25);/q;+1/p-1/t10-,11-,12+,13-,15+;/m0./s1
SMILES	C1=CC2=C(C=C1OC3C(C(C(C(O3)C(=O)[O-])O)O)O)OC(=O)C=C2C(F)(F)F.[K+]
Synonyms	2-Oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl β-D-Glucopyranosiduronic Acid Monopotassium Salt; 4-Trifluoromethyl-7-hydroxycoumarin Glucuronide;