137629-36-8 ,2-Nitrophenyl b-D-glucuronide,CAS:137629-36-8

137629-36-8 ,2-Nitrophenyl b-D-glucuronide,
CAS:137629-36-8
C12H13NO9 / 315.23
MFCD00152148

2-Nitrophenyl b-D-glucuronide

2-Nitrophenyl-b-D-glucuronide is a chromogenic substrate used to detect the activity of beta-glucuronidase in various biological samples. Upon hydrolysis by the enzyme, the substrate releases 2-nitrophenol, which can be spectrophotometrically measured at 405 nm. The substrate is commonly used in clinical assays to evaluate liver and kidney function, as well as in drug metabolism studies. It is also used in environmental monitoring to assess the presence of microbial activity in soil and water samples. Overall, 2-Nitrophenyl-b-D-glucuronide is a widely used substrate with excellent sensitivity and specificity, making it a valuable tool in enzymology research and diagnostic testing.

CAS Number	137629-36-8
Product Name	(2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(2-nitrophenoxy)tetrahydro-2H-pyran-2-carboxylic acid
IUPAC Name	(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(2-nitrophenoxy)oxane-2-carboxylic acid
Molecular Formula	C12H13NO9
Molecular Weight	315.23 g/mol
InChI	InChI=1S/C12H13NO9/c14-7-8(15)10(11(17)18)22-12(9(7)16)21-6-4-2-1-3-5(6)13(19)20/h1-4,7-10,12,14-16H,(H,17,18)/t7-,8-,9+,10-,12+/m0/s1
InChI Key	UADVJQJTJSOJOQ-GOVZDWNOSA-N
SMILES	C1=CC=C(C(=C1)[N+](=O)[O-])OC2C(C(C(C(O2)C(=O)O)O)O)O
Synonyms	2-Nitrophenyl β-D-Glucopyranosiduronic Acid;
Canonical SMILES	C1=CC=C(C(=C1)[N+](=O)[O-])OC2C(C(C(C(O2)C(=O)O)O)O)O
Isomeric SMILES	C1=CC=C(C(=C1)[N+](=O)[O-])O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C(=O)O)O)O)O