13199-25-2 , 2,3-O-异亚丙基-D-呋喃核糖,
2,3-o-isopropylidene-d-ribofuranose,
CAS:13199-25-2
C8H14O5 /190.19
MFCD01075718
2,3-o-isopropylidene-d-ribofuranose,
(4R,5R)-5-((R)-1,2-Dihydroxyethyl)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde is a compound that belongs to the class of organic compounds known as aldoses. An aldose is a monosaccharide that contains an aldehyde group at the terminal carbon. (4R,5R)-5-((R)-1,2-Dihydroxyethyl)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde is also known as DDDC. Chemically, it has the molecular formula C9H14O6 and a molecular weight of 218.21 g/mol.
Synthesis and Characterization:
(4R,5R)-5-((R)-1,2-Dihydroxyethyl)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde can be synthesized by reacting diethylene glycol with acetone in the presence of acid catalysts. The product obtained is then treated with sodium borohydride, which reduces the carbonyl group to an alcohol. This alcohol is then oxidized to the aldehyde using a powerful oxidizing agent. DDDC can be characterized using various spectroscopic techniques like IR, NMR, and Mass spectrometry.
Analytical Methods:
The most commonly used analytical methods for the detection and quantification of (4R,5R)-5-((R)-1,2-Dihydroxyethyl)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde are High-Performance Liquid Chromatography (HPLC), Gas Chromatography-Mass Spectrometry (GC-MS), and Ultraviolet-visible Spectroscopy (UV-Vis).
Biological Properties:
In recent years, (4R,5R)-5-((R)-1,2-Dihydroxyethyl)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde has gained considerable attention due to its biological properties. It has been shown to possess anti-inflammatory, anticancer, and antioxidant properties in various in-vitro studies. DDDC has also been found to reduce the oxidative damage caused by the reactive oxygen species (ROS), which can cause various diseases and disorders.
Toxicity and Safety in Scientific Experiments:
The toxicity profile of (4R,5R)-5-((R)-1,2-Dihydroxyethyl)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde has been extensively studied. It has been found to be relatively safe and non-toxic at lower doses. However, at higher doses, it can cause liver damage, respiratory problems, and central nervous system depression. Therefore, it is recommended to use (4R,5R)-5-((R)-1,2-Dihydroxyethyl)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde only under the supervision of a qualified healthcare professional.
Applications in Scientific Experiments:
(4R,5R)-5-((R)-1,2-Dihydroxyethyl)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde has been extensively used in various scientific experiments. It has been used as an antioxidant, as a reactant in the synthesis of various organic compounds, and as a reducing agent in various chemical reactions. It has also been used in the preparation of various pharmaceuticals.
Current State of Research:
(4R,5R)-5-((R)-1,2-Dihydroxyethyl)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde has been extensively studied in recent years. There is a growing body of evidence that suggests that DDDC possesses various biological properties and has potential applications in various scientific fields.
Potential Implications in Various Fields of Research and Industry:
(4R,5R)-5-((R)-1,2-Dihydroxyethyl)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde has potential implications in various fields of research and industry. It can be used as an antioxidant in the food industry, as a reducing agent in the chemical industry, and as a reactant in the synthesis of various pharmaceuticals. It also has potential applications in the treatment of various diseases and disorders.
Limitations and Future Directions:
One of the main limitations of (4R,5R)-5-((R)-1,2-Dihydroxyethyl)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde is its low solubility in water. This limits its application in various scientific experiments. Another limitation is its potential toxicity at higher doses. Future research should focus on synthesizing new derivatives of DDDC that have improved solubility and reduced toxicity. Future research should also focus on the potential applications of DDDC in various fields of research and industry.
Future Directions:
1. Synthesis of new derivatives of DDDC with improved solubility and reduced toxicity.
2. Clinical studies to test the efficacy of DDDC in the treatment of various diseases and disorders.
3. Investigation of the potential applications of DDDC in the food and chemical industry.
4. Development of new analytical methods for the detection and quantification of DDDC.
5. Use of DDDC in the synthesis of new pharmaceuticals with improved efficacy and reduced side effects.
CAS Number | 13199-25-2 |
Product Name | (4R,5R)-5-((R)-1,2-Dihydroxyethyl)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde |
IUPAC Name | (4R,5R)-5-[(1R)-1,2-dihydroxyethyl]-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde |
Molecular Formula | C₈H₁₄O₅ |
Molecular Weight | 190.19 |
InChI | InChI=1S/C8H14O5/c1-8(2)12-6(4-10)7(13-8)5(11)3-9/h4-7,9,11H,3H2,1-2H3/t5-,6+,7-/m1/s1 |
SMILES | CC1(OC(C(O1)C(CO)O)C=O)C |
Synonyms | 2,3-O-(1-Methylethylidene)-D-ribose; |
CAS No: 13199-25-2,4099-88-1 MDL No: MFCD01075718 Chemical Formula: C8H14O5 Molecular Weight: 190.19 |
References: 1. Burnett LA, Howie RA, Garden SJ, Rufino H, Wardell JL, J. Chem. Res. 1998, p418-419 |
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