10357-27-4, 对硝基苯基-a-D-甘露糖苷,Man-a-PNP, CAS: 10357-27-4

1Man-a-PNP,
对硝基苯基-a-D-甘露糖苷，
4-Nitrophenyl alpha-D-mannopyranoside,
CAS: 10357-27-4
C12H15NO8 / 301.25
MFCD00066002

4-Nitrophenyl a-D-mannopyranoside

对硝基苯基-a-D-甘露糖苷

4-Nitrophenyl a-D-mannopyranoside is a chromogenic pNP enzyme substrate that enables the detection and quantification of a-D-mannosidase activity in various biological samples through a colorimetric assay. The hydrolysis of the substrate by the enzyme releases 4-nitrophenol, a yellow compound whose absorption can be measured spectrophotometrically. Applications for this substrate span biomedical research, disease diagnostics, and industrial enzyme production.

CAS No: 10357-27-4 Synonyms: Man-a-PNP MDL No: MFCD00066002 Chemical Formula: C12H15NO8 Molecular Weight: 301.25

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CAS Number	10357-27-4
Product Name	4-Nitrophenyl a-D-mannopyranoside
IUPAC Name	(2R,3S,4S,5S,6R)-2-(hydroxymethyl)-6-(4-nitrophenoxy)oxane-3,4,5-triol
Molecular Formula	C12H15NO8
Molecular Weight	301.25 g/mol
InChI	InChI=1S/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9-,10+,11+,12+/m1/s1
InChI Key	IFBHRQDFSNCLOZ-GCHJQGSQSA-N
SMILES	C1=CC(=CC=C1[N+](=O)[O-])OC2C(C(C(C(O2)CO)O)O)O
Synonyms	4'-nitrophenyl-alpha-D-mannopyranoside, 4-nitrophenyl-alpha-D-mannopyranoside, alpha-PNM, p-nitrophenyl-alpha-mannoside, para-nitrophenyl-alpha-D-mannopyranoside, PNPAM
Canonical SMILES	C1=CC(=CC=C1[N+](=O)[O-])OC2C(C(C(C(O2)CO)O)O)O
Isomeric SMILES	C1=CC(=CC=C1[N+](=O)[O-])O[C@@H]2[C@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O

COA:

Name: 4-Nitrophenyl alpha-D-mannopyranoside

CAS: 10357-27-4 M.F.: C₁₂H₁₅NO₈ M.W.: 301.25

*Items*	*Standards*	*Results*
Appearance	White crystalline power	Positive
Solubility	Soluble in water and insoluble in ether	Positive
NMR and MS	Should comply	Complies
Identification	IR and TLC	Positive
M.P.	180℃ -185℃	180℃ -184℃
[a]^D [c=0.44 inH₂O].	+150^o - +160^o	+155.2^o
Loss Weight On Dryness	Max. 0.5%	Complies
Beta-Isomer	Max. 0.5%	0.4%
TLC (15%H₂SO₄-C₂H₅OH)	One spot	Complies
Assay (HPLC)	Min. 98%	99.6%